3D Genome Tuner: Compare Multiple Circular Genomes in a 3D Context

Circular genomes, being the largest proportion of sequenced genomes, play an important role in genome analysis. However, traditional 2D circular map only provides an overview and annotations of genome but does not offer feature-based comparison. For remedying these shortcomings, we developed 3D Genome Tuner, a hybrid of circular map and comparative map tools. Its capability of viewing comparisons between multiple circular maps in a 3D space offers great benefits to the study of comparative genomics. The program is freely available(under an LGPL licence)at http://sourceforge.net/projects/dgenometuner.

作 者： Qi Wang Qun Liang Xiuqing Zhang   作者單位： Qi Wang,Qun Liang(Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China;Graduate University of Chinese Academy of Sciences, Beijing 100049, China)

Xiuqing Zhang(Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China;Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China) 

刊 名： 基因組蛋白質(zhì)組與生物信息學(xué)報（英文版）  英文刊名： GENOMICS、PROTEOMICS & BIOINFORMATICS  年，卷(期)： 2009 7(3)  分類號： Q5  關(guān)鍵詞： three dimensional   circular map   genome browser   comparative genomics  

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